All Diablo 4 Endgame boss Unique loot tables in Season 4

Amitesh Dhar
Andariel Diablo 4

Diablo 4 Season 4: Loot Reborn is here and players are eager to try out the revamped endgame experience. So here’s everything you need to know about the endgame boss loot tables and their Unique rewards.

Getting hold of Uber Unique items in Diablo 4 Season 4 can be one of the biggest achievements for many players in the game. Thanks to the presence of such endgame bosses, you can invest plenty of time and dedication to get your favorite Uber Unique item.

To help you target farm Uniques, here’s a list of all Diablo 4 Season 4: Loot Reborn endgame bosses and their Unique loot tables.

All Diablo 4 endgame boss loot tables

Echo of Varshan loot table

Varshan in Diablo 4
The Echo of Varshan is a formidable foe.

How to summon: Collect different Malignant body parts (Gurgling Head, Trembling Hand, Malignant Heart, Blackened Femur.)

You can collect the parts above from the Tree of Wishpers caches. Once you’ve collected all the items, head into the Malignant Burrow below the Tree of Whispers to summon this boss. Once you defeat it, you can claim the following Unique rewards:

ClassUnique
SorcererTal Rasha’s Iridescent Loop, Staff of Endless Rage, Esu’s Heirloom, Raiment of the Infinite
DruidAiridah’s Inexorable Will, Mad Wolf’s Glee, Vasily’s Prayer, Greatstaff of the Crone
BarbarianRing of Red Furor, Fields of Crimson, 100,000 Steps, Gohr’s Devastating Grips
NecromancerRing of the Sacrilegious Soul, Bloodless Scream, Deathless Visage, Deathspeaker’s Pendant
RogueWrithing Band of Trickery, Condemnation, Eyes in the Dark, Skyhunter
All classesFrostburn, Mother’s Embrace

Grigoire, the Galvanic Saint loot table

Grigoire Diablo 4
Grigoire, the Galvanic Saint can drop certain Uniques like the Hunter’s Zenith.

How to summon: Collect Living Steel from Helltides

Once you’ve collected enough Living Steel, make your way to the Hall of the Pentinent dungeon in Dry Steppes. You’ll need two Living Steel to summon him in World Tier 3, and five Living Steel to summon him in World Tier 4 in Diablo 4. You can check out the Uniques for Grigoire in the following table:

ClassUnique
SorcererStaff of Lam Esen, Iceheart Brais, Gloves of the Illuminator
DruidInsatiable Fury, Hunter’s Zenith, Waxing Gibbous, The Butcher’s Cleaver
BarbarianRamaladni’s Magnum Opus, Rage of Harrogath, Ancients’ Oath, Battle Trance, The Butcher’s Cleaver
NecromancerBlood Artisan’s Cuirass, Howl from Below, Greaves of the Empty Tomb
RogueWord of Hakan, Grasp of Shadow, Windforce
All classesPenitent Greaves

Lord Zir loot table

Lord Zir in Diablo 4
Lord Zir is one of the most difficult bosses in Diablo 4.

How to summon: Collect Exquisite Blood from Legion Events.

Although he was the boss in the past Season of Blood, you will still be able to summon him in the game. Head to The Ancient Seat in Fractured Peaks to summon Zir, and check out the Uniques that he drops when defeated:

ClassUnique
SorcererStaff of Endless Rage, Iceheart Brais, Raiment of the Infinite, Esadora’s Overflowing Cameo
DruidMad Wolf’s Glee, Vasily’s Prayer, Greatstaff of the Crone, Fleshrender, The Butcher’s Cleaver
BarbarianRamaladni’s Magnus Opus, Rage of Harrogath, Gohr’s Devastating Grips, Overkill, The Butcher’s Cleaver
NecromancerBlood Artisan’s Cuirass, Deathless Visage, Greaves of the Empty Tomb, Lidless Wall
RogueGrasp of Shadow, Eyes in the Dark, Skyhunter, Asheara’s Khanjar
All classesPenitent Greaves, Razorplate, Temerity

The Beast in Ice loot table

Diablo 4 Season 2 Beast in Ice
Beast in Ice is an extremely formidable enemy in the game.

How to summon: Collect Distilled Fear by completing Tier 30 Nightmare Dungeons.

Once you’ve collected enough Distilled Fear, make your way to the Occultist in Diablo 4 to craft the Glacial Fissure Nightmare Sigil. Here are the Uniques that you can get by defeating The Beast in Ice boss in Diablo 4:

ClassUnique
SorcererStaff of Lam Esen, Esu’s Heirloom, Gloves of the Illuminator, The Oculus, Starfall Coronet
DruidInsatiable Fury, Hunter’s Zenith, Waxing Gibbous, Storm’s Companion, Unsung Ascetic’s Wraps
BarbarianFields of Crimson, 100,000 Steps, Ancients’ Oath, Battle Trance, Hellhammer, Ring of the Ravenous
NecromancerBloodless Scream, Howl from Below, Deathspeaker’s Pendant, Ring of Mendeln, Mutilator Plate
RogueCondemnation, Word of Hakan, Windforce, Eaglehorn, Beastfall Boots
All classesFrostburn, Mother’s Embrace, Fists of Fate, Tassets of Dawning Sky, Paingorger’s Gauntlets

Duriel, King of Maggots loot table

Echo of Duriel Diablo 4 Season 2
You can get Tibault’s Will by defeating Duriel.

How to summon: Collect Mucus-Slick Eggs and Shards of Agony by defeating Varshan and Grigoire respectively.

It’s worth remembering that the Mucus-Slick Eggs are only available in World Tier 4. So once you’ve collected the two items, you need to make your way to the Gaping Crevasse dungeon and find the altar to summon Duriel.

Duriel is the only boss in the game that drops Uber Uniques, so you should farm the fight whenever you can.

ClassUnique
SorcererFlamescar, Blue Rose
DruidTempest Roar, Dolmen Stone
BarbarianAzurewrath, Tuskhelm of Joritz the Mighty
NecromancerBlack River, Blood Moon Breeches
RogueCowl of the Nameless, Scoundrel’s Leathers
All classesGodslayer Crown, Flickerstep, Tibault’s Will, X’Fal’s Corroded Signet, Soulbrand, Banished Lord’s Talisman
Uber UniquesDoombringer (Barbarian, Necromancer, Rogue), The Grandfather (Barbarian, Necromancer), Melted Heart of Selig, Andariel’s Visage, Harlequin Crest, Ring of Starless Skies, Abavarion, Spear of Lycander (Druid, Sorcerer)

Echo of Andariel, Maiden of Anguish loot table

Andariel the Maiden of Anguish in Diablo 4
You’ll need to take on two Uber bosses before fighting Andariel.

How to summon: Collect Sandscorched Shackles in Diablo 4 Season 4 from Lord Zir, and Pincushioned Dolls from The Beast in Ice to summon her.

Needlessly to say, you’ll have to be in World Tier 4 to summon her, and the jump in difficulty compared to her base version in the campaign is massive. Once you have these items, make your way to Hanged Man’s Hall to summon her.

Alongside Duriel, she will also drop Uber Unique items so it should be worthwhile farming her and getting your hands on the best items available in the game.

ClassUnique
SorcererFlamescar, Blue Rose
DruidTempest Roar, Dolmen Stone
BarbarianAzurewrath, Tuskhelm of Joritz the Mighty
NecromancerBlack River, Blood Moon Breeches
RogueCowl of the Nameless, Scoundrel’s Leathers
All classesTyrael’s Might, Godslayer Crown, Flickerstep, Tibault’s Will, X’Fal’s Corroded Signet, Soulbrand, Banished Lord’s Talisman
Uber UniquesDoombringer (Barbarian, Necromancer, Rogue), The Grandfather (Barbarian, Necromancer), Melted Heart of Selig, Andariel’s Visage, Harlequin Crest, Ring of Starless Skies, Abavarion, Spear of Lycander (Druid, Sorcerer)

If you are interested in Diablo 4, here are more of our guides you can have a look at:

Best Diablo 4 Druid builds | Best Diablo 4 Barbarian build | Diablo 4 skill tree builder | Is Diablo 4 coming to Nintendo Switch | How to fast travel in Diablo 4 | Is Diablo 4 playable on the Steam Deck | How to salvage gear in Diablo 4 | How to transmog gear in Diablo 4 | Diablo 4 Ashava boss guide | Diablo 4 server status

About The Author

Amitesh started writing about video games in 2020. He previously worked at Sportskeeda, Gfinity, and Attack of the Fanboy before joining CharlieIntel in 2024. He's an avid fan of Destiny 2 and Diablo 4 and an expert on all things Fortnite. You can get in touch with him at [email protected].